DNA probe for the identification of Histoplasma capsulatum.

نویسندگان

  • E J Keath
  • E D Spitzer
  • A A Painter
  • S J Travis
  • G S Kobayashi
  • G Medoff
چکیده

A 1.85-kilobase HindIII nuclear DNA probe from Histoplasma capsulatum G217B detected polymorphic restriction fragments within whole-cell DNA from different clinical isolates of H. capsulatum, consistent with the previous system of classification. The probe failed to hybridize to DNA from Blastomyces dermatitidis, Candida spp., Saccharomyces cerevisiae, Sepedonium chrysospermum, and Chrysosporium keratinophilum under low-stringency conditions and therefore may have value as a diagnostic reagent to identify H. capsulatum.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 27 10  شماره 

صفحات  -

تاریخ انتشار 1989